Titanium Dioxide is suspected of causing endocrine-disrupting effects, according to European Commission Annex 13. Includes both Category 1 (evidence for endocrine disruption in living organisms) and Category 2 (evidence of potential to cause endocrine disruption in in vitro studies)
Titanium Dioxide is suspected of causing asthma. This list is a compilation of various sources including those that "may cause sensitization by inhalation" and includes some agents that are identified according to the Association of Occupational and Environmental Clinics (AOEC) as asthmagens or chemicals of concern for their potential to cause asthma.
Titanium Dioxide is suspected of causing cancer, according to official classification designated under an EU regulation known as EU - CLP (1272/2008) as well as those designated by the International Agency for the Research on Cance (IARC) as IARC Group 2B (Possibly Carcinogenic to Humans) substances.
"Titanium Dioxide is known to cause cancer, according to the State of California (Proposition 65) and/or an official classifications of Carcinogen Category 1A and 1B as defined under an EU regulation known as EU - CLP (1272/2008) and/or WHMIS 2015 classifications as provided by the Commission des normes, de l'equite, de la sante et de la securite du travail, (Sante et de la securite du travai service du repertoire toxicologique) in Quebec.