Isoeugenol is suspected of causing endocrine-disrupting effects, according to European Commission Annex 13. Includes both Category 1 (evidence for endocrine disruption in living organisms) and Category 2 (evidence of potential to cause endocrine disruption in in vitro studies)
Isoeugenol is suspected of causing asthma. This list is a compilation of various sources including those that "may cause sensitization by inhalation" and includes some agents that are identified according to the Association of Occupational and Environmental Clinics (AOEC) as asthmagens or chemicals of concern for their potential to cause asthma.
Isoeugenol is a suspected neurotoxin.
Isoeugenol is suspected of causing neurotoxicity, according to various official national and internation hazard classification systems and/or by being recognized under EPA - IRIS Inhalation Reference Concentration (RfC) list and/or EPA - IRIS Oral Reference Dose (RfD) as having appropriate critical effects.
Isoeugenol can cause contact allergies in fragrance-sensitive consumers, according to the European Union.
Isoeugenol is subject to restrictions on use in fragrances under standards issued by the International Fragrance Association. Most restrictions are based on concentration or product-type where fragrance is found.
Isoeugenol has been restricted in cosmetics use by the European Union.