Usnic Acid Guide

Usnic acid is a naturally occurring dibenzofuran derivative found in several lichen species. It was first isolated by German scientist W. Knop in 1844[1] and first synthesized between 1933-1937 by Curd and Robertson.[2] Usnic acid was identified in many genera of lichens including Usnea, Cladonia, Lecanora, Ramalina, Evernia, Parmelia and Alectoria. Although it is generally believed that usnic acid is exclusively restricted to lichens, in a few unconfirmed isolated cases the compound was found in kombucha tea and non-lichenized ascomycetes.

At normal conditions, usnic acid is a bitter, yellow, solid substance. It is known to occur in nature in both the d- and l-forms as well as a racemic mixture....